- pregnancy - previous allergic reaction to immunoglobulin treatment - ig a deficiency - patient requiring 2 inotropic agents to maintain blood pressures - known case of any autoimmune disorder - acute kidney injury or chronic renal failure - known case of thromboembolic disorder - aseptic meningitis

- pregnancy - previous allergic reaction to immunoglobulin treatment - ig a deficiency - patient requiring 2 inotropic agents to maintain blood pressures - known case of any autoimmune disorder - acute kidney injury or chronic renal failure - known case of thromboembolic disorder - aseptic meningitis