- active covid-19 disease - prior covid-19 disease - current fever, cough, shortness of breath - allergy to chloroquine or hydroxychloroquine - prior retinal eye disease - known chronic kidney disease, stage 4 or 5 or dialysis - known glucose-6 phosphate dehydrogenase (g-6-pd) deficiency - weight <40 kg - prolonged qt syndrome - current use of hydroxychloroquine, chloroquine, or cardiac medicines of flecainide, amiodarone, digoxin, procainamide, or propafenone - current use of medications with known significant drug-drug interactions: artemether, lumefantrine, mefloquine, tamoxifen, or methotrexate.

- active covid-19 disease - prior covid-19 disease - current fever, cough, shortness of breath - allergy to chloroquine or hydroxychloroquine - prior retinal eye disease - known chronic kidney disease, stage 4 or 5 or dialysis - known glucose-6 phosphate dehydrogenase (g-6-pd) deficiency - weight <40 kg - prolonged qt syndrome - current use of hydroxychloroquine, chloroquine, or cardiac medicines of flecainide, amiodarone, digoxin, procainamide, or propafenone - current use of medications with known significant drug-drug interactions: artemether, lumefantrine, mefloquine, tamoxifen, or methotrexate.