Proportion of participants alive and free of respiratory failure at Day 28. Participants are alive and free of respiratory failure if they are in category 1; 2; 3 or 4 from the GlaxoSmithKline (GSK) modified version ordinal scale adapted from World Health Organization (WHO) scale 2020. The 8-point scale is as follows: 1) Non-hospitalized; no limitation of activity; 2) Non-hospitalized; limitation of activity; 3) Hospitalized; no oxygen therapy; 4) Hospitalized; low-flow oxygen by mask or nasal prongs; 5) Hospitalized; high-flow oxygen (=15L/min); continuous positive airway pressure (CPAP); bilevel positive airway pressure (BIPAP); non-invasive ventilation; 6) Hospitalized; intubation and mechanical ventilation; 7) Hospitalized; mechanical ventilation plus additional organ support; 8) Death.

Proportion of participants alive and free of respiratory failure at Day 28. Participants are alive and free of respiratory failure if they are in category 1; 2; 3 or 4 from the GlaxoSmithKline (GSK) modified version ordinal scale adapted from World Health Organization (WHO) scale 2020. The 8-point scale is as follows: 1) Non-hospitalized; no limitation of activity; 2) Non-hospitalized; limitation of activity; 3) Hospitalized; no oxygen therapy; 4) Hospitalized; low-flow oxygen by mask or nasal prongs; 5) Hospitalized; high-flow oxygen (=15L/min); continuous positive airway pressure (CPAP); bilevel positive airway pressure (BIPAP); non-invasive ventilation; 6) Hospitalized; intubation and mechanical ventilation; 7) Hospitalized; mechanical ventilation plus additional organ support; 8) Death.