1. Alanine Transaminase (ALT) or Aspartate Transaminase (AST) > 5 times the upper limit of normal. 2. Reduced renal function with estimated glomerular filtration rate (eGFR) < 30 ml/min or hemodialysis or hemofiltration. 3. Pregnancy or breast feeding. 4. Evidence of multiorgan failure 5. Steroid treatment by any reason within 72 hours prior to enrolment 6. Participation in any other clinical trial of an experimental agent treatment for COVID-19 7. Physician makes a decision that trial involvement is not in patients' best interest, or any condition that does not allow the protocol to be followed safely.

1. Alanine Transaminase (ALT) or Aspartate Transaminase (AST) > 5 times the upper limit of normal. 2. Reduced renal function with estimated glomerular filtration rate (eGFR) < 30 ml/min or hemodialysis or hemofiltration. 3. Pregnancy or breast feeding. 4. Evidence of multiorgan failure 5. Steroid treatment by any reason within 72 hours prior to enrolment 6. Participation in any other clinical trial of an experimental agent treatment for COVID-19 7. Physician makes a decision that trial involvement is not in patients' best interest, or any condition that does not allow the protocol to be followed safely.