inclusion criteria: a. male or female, at least 18 years old. b. admitted to the hospital and placed on high flow oxygen (greater than 6l by nasal cannula or mask delivery system) or intubated for the treatment of (established or presumed) covid-19. c. informed consent provided by the patient or health care proxy. d. confirmation of sars-cov-2 infection by pcr or rapid antigen testing for sars-cov-2 infection prior to randomization.

inclusion criteria: a. male or female, at least 18 years old. b. admitted to the hospital and placed on high flow oxygen (greater than 6l by nasal cannula or mask delivery system) or intubated for the treatment of (established or presumed) covid-19. c. informed consent provided by the patient or health care proxy. d. confirmation of sars-cov-2 infection by pcr or rapid antigen testing for sars-cov-2 infection prior to randomization.

inclusion criteria: a. male or female, at least 18 years old. b. admitted to the hospital and placed on high flow oxygen (greater than 6l by nasal cannula or mask delivery system) or intubated for the treatment of (established or presumed) covid-19. c. informed consent provided by the patient or health care proxy. d. confirmation of sars-cov-2 infection by pcr prior to randomization.

inclusion criteria: a. male or female, at least 18 years old. b. admitted to the hospital and placed on high flow oxygen (greater than 6l by nasal cannula or mask delivery system) or intubated for the treatment of (established or presumed) covid-19. c. informed consent provided by the patient or health care proxy. d. confirmation of sars-cov-2 infection by pcr prior to randomization.