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June 4, 2022, 10:30 a.m. eu

Participants are excluded from the study if any of the substudy-specific exclusion criteria apply. Some exclusion criteria are common to all substudies: participants with medical or psychiatric conditions that may increase the risk of study participation, history of severe adverse reactions associated with a vaccine and/or severe allergic reaction to any component of the study vaccination, previous clinical or microbiological diagnosis of COVID-19, immunocompromised individuals, or participants with bleeding diathesis. For Substudy A, see Section 10.7.5.2. of the Study Protocol. For Substudy B, see Section 10.8.5.2. of the Study Protocol. For Substudy C, see Section 10.9.5.2. of the Study Protocol. For Substudy D, see Section 10.10.5.2. of the Study Protocol. For Substudy E, see Section 10.11.5.2. of the Study Protocol. For Substudy F, see Section 10.12.5.2. of the Study Protocol.

Participants are excluded from the study if any of the substudy-specific exclusion criteria apply. Some exclusion criteria are common to all substudies: participants with medical or psychiatric conditions that may increase the risk of study participation, history of severe adverse reactions associated with a vaccine and/or severe allergic reaction to any component of the study vaccination, previous clinical or microbiological diagnosis of COVID-19, immunocompromised individuals, or participants with bleeding diathesis. For Substudy A, see Section 10.7.5.2. of the Study Protocol. For Substudy B, see Section 10.8.5.2. of the Study Protocol. For Substudy C, see Section 10.9.5.2. of the Study Protocol. For Substudy D, see Section 10.10.5.2. of the Study Protocol. For Substudy E, see Section 10.11.5.2. of the Study Protocol. For Substudy F, see Section 10.12.5.2. of the Study Protocol.

March 1, 2022, 8:58 p.m. eu

Participants are excluded from the study if any of the substudy-specific exclusion criteria apply. Some exclusion criteria are common to all substudies: participants with medical or psychiatric conditions that may increase the risk of study participation, history of severe adverse reactions associated with a vaccine and/or severe allergic reaction to any component of the study vaccination, previous clinical or microbiological diagnosis of COVID-19, immunocompromised individuals, or participants with bleeding diathesis. For Substudy A, see Section 10.7.5.2. of the Study Protocol, For Substudy B, see Section 10.8.5.2. of the Study Protocol, For Substudy C, see Section 10.9.5.2. of the Study Protocol.

Participants are excluded from the study if any of the substudy-specific exclusion criteria apply. Some exclusion criteria are common to all substudies: participants with medical or psychiatric conditions that may increase the risk of study participation, history of severe adverse reactions associated with a vaccine and/or severe allergic reaction to any component of the study vaccination, previous clinical or microbiological diagnosis of COVID-19, immunocompromised individuals, or participants with bleeding diathesis. For Substudy A, see Section 10.7.5.2. of the Study Protocol, For Substudy B, see Section 10.8.5.2. of the Study Protocol, For Substudy C, see Section 10.9.5.2. of the Study Protocol.