Primary Efficacy Endpoint Main Study The proportion of patients that are alive and without any need for oxygen support defined as a score of 3 or less in the above scale. The primary endpoint will be assessed at 28-days after treatment initiation. Sub (Exploratory) Study The cumulative mortality rate at 60 days after treatment initiation.

Primary Efficacy Endpoint Main Study The proportion of patients that are alive and without any need for oxygen support defined as a score of 3 or less in the above scale. The primary endpoint will be assessed at 28-days after treatment initiation. Sub (Exploratory) Study The cumulative mortality rate at 60 days after treatment initiation.