1. Willing and able to provide written informed consent prior to performing study procedures 2. SARS-CoV-2 positivity of the nasal/throat-swab/saliva swab by reverse-transcriptase-polymerase chain- reaction (RT-PCR) assay tested by the local diagnostic laboratory ≤ 4 days before randomization 3. Currently hospitalized or requiring hospitalization for the COVID-19 medical care 4. Age >18 and <85 years 5. Presence of at least 3 of the following symptoms as present: fever, cough, myalgia, fatigue 6. Saturation of oxygen (SpO2) > 93%, with or without oxygen therapy ≤ 2 days before screening 7. Agree to use an acceptable method of contraception for the duration of the study or not be of childbearing potential. Acceptable methods of birth control include: spermicide with barrier, oral, transdermal, injectable, or implantable contraception, IUD, abstinence, and surgical sterilization of partner. Female subjects are not of childbearing potential if they have had a hysterectomy, bilateral oophorectomy, bilateral tubal ligation, or are post-menopausal by at least 12 months.

1. Willing and able to provide written informed consent prior to performing study procedures 2. SARS-CoV-2 positivity of the nasal/throat-swab/saliva swab by reverse-transcriptase-polymerase chain- reaction (RT-PCR) assay tested by the local diagnostic laboratory ≤ 4 days before randomization 3. Currently hospitalized or requiring hospitalization for the COVID-19 medical care 4. Age >18 and <85 years 5. Presence of at least 3 of the following symptoms as present: fever, cough, myalgia, fatigue 6. Saturation of oxygen (SpO2) > 93%, with or without oxygen therapy ≤ 2 days before screening 7. Agree to use an acceptable method of contraception for the duration of the study or not be of childbearing potential. Acceptable methods of birth control include: spermicide with barrier, oral, transdermal, injectable, or implantable contraception, IUD, abstinence, and surgical sterilization of partner. Female subjects are not of childbearing potential if they have had a hysterectomy, bilateral oophorectomy, bilateral tubal ligation, or are post-menopausal by at least 12 months.