● Population at risk of developing severe COVID-19, defined as either: Age ≥ 40 years of age Age ≥ 18 years of age and at least one known comorbidity Age ≥ 18 years of age and a BMI ≥ 30 ● COVID-19 disease confirmed by the presence of SARS-CoV-2 nucleic acid by polymerase chain reaction (PCR) within 5 days prior to inclusion. ● For women of childbearing age (defined as non-sterile premenopausal women): Negative pregnancy test and willingness to use contraceptive during the study period (90 days) ● Provision of informed consent.

● Population at risk of developing severe COVID-19, defined as either: Age ≥ 40 years of age Age ≥ 18 years of age and at least one known comorbidity Age ≥ 18 years of age and a BMI ≥ 30 ● COVID-19 disease confirmed by the presence of SARS-CoV-2 nucleic acid by polymerase chain reaction (PCR) within 5 days prior to inclusion. ● For women of childbearing age (defined as non-sterile premenopausal women): Negative pregnancy test and willingness to use contraceptive during the study period (90 days) ● Provision of informed consent.

● Population at risk of developing severe COVID-19, defined as either: Age ≥ 50 years of age Age ≥ 18 years of age and at least one known comorbidity Age ≥ 18 years of age and a BMI ≥ 30 ● COVID-19 disease confirmed by the presence of SARS-CoV-2 nucleic acid by polymerase chain reaction (PCR) within 5 days prior to inclusion. ● For women of childbearing age (defined as non-sterile premenopausal women): Negative pregnancy test and willingness to use contraceptive during the study period (90 days) ● Provision of informed consent.

● Population at risk of developing severe COVID-19, defined as either: Age ≥ 50 years of age Age ≥ 18 years of age and at least one known comorbidity Age ≥ 18 years of age and a BMI ≥ 30 ● COVID-19 disease confirmed by the presence of SARS-CoV-2 nucleic acid by polymerase chain reaction (PCR) within 5 days prior to inclusion. ● For women of childbearing age (defined as non-sterile premenopausal women): Negative pregnancy test and willingness to use contraceptive during the study period (90 days) ● Provision of informed consent.