•Binding antibody concentrations to SARS CoV-2 S protein as measured by ELISA 28 days after vaccination •NI will be demonstrated in terms of humoral immune response expressed by the GMCs of S-ELISA, 28 days post-dose 1, using a NI margin of 2/3 for the GMC ratio (GMC 2.5x1010 [or 1.25x1010 vp]/GMC 5x1010 vp) •Binding antibody concentrations to SARS CoV-2 S protein as measured by ELISA 28 days after vaccination 2 •NI will be demonstrated in terms of humoral immune response expressed by the GMCs of S-ELISA, 28 days post-dose 2 (2.5x1010 vp or 1.25x1010 vp) and 28 days post-dose 1 or 2 (5x1010 vp), using a NI margin of 2/3 for the GMC ratio (GMC 2.5x1010 [or 1.25x1010 vp]/GMC 5x1010 vp)

•Binding antibody concentrations to SARS CoV-2 S protein as measured by ELISA 28 days after vaccination •NI will be demonstrated in terms of humoral immune response expressed by the GMCs of S-ELISA, 28 days post-dose 1, using a NI margin of 2/3 for the GMC ratio (GMC 2.5x1010 [or 1.25x1010 vp]/GMC 5x1010 vp) •Binding antibody concentrations to SARS CoV-2 S protein as measured by ELISA 28 days after vaccination 2 •NI will be demonstrated in terms of humoral immune response expressed by the GMCs of S-ELISA, 28 days post-dose 2 (2.5x1010 vp or 1.25x1010 vp) and 28 days post-dose 1 or 2 (5x1010 vp), using a NI margin of 2/3 for the GMC ratio (GMC 2.5x1010 [or 1.25x1010 vp]/GMC 5x1010 vp)