- Sars-CoV-2 infection based on: highly clinical suspicion on admission and/or positive PCR test on naso¬pharynx swab or sputum and/or a CT imaging of the chest compatible with COVID-19 + type 1 or type 2 respiratory failure despite supplemental oxygen that indicates airway support/ICU admittance and meeting any of the following criteria: . - SpO2 <90% or PaO2/FiO2 < 200 mmHg - Clinical evidence of respiratory distress (RR > 25 breaths/minute)

- Sars-CoV-2 infection based on: highly clinical suspicion on admission and/or positive PCR test on naso¬pharynx swab or sputum and/or a CT imaging of the chest compatible with COVID-19 + type 1 or type 2 respiratory failure despite supplemental oxygen that indicates airway support/ICU admittance and meeting any of the following criteria: . - SpO2 <90% or PaO2/FiO2 < 200 mmHg - Clinical evidence of respiratory distress (RR > 25 breaths/minute)