• Population: All study participants fulfilling the inclusion and exclusion criteria • Target variable: Clinical severity status on a 7-point ordinal scale at Day 15 • Estimator: Odds ratio of ATR-002 in addition to standard of care versus placebo in addition to standard of care with 95% confidence interval

• Population: All study participants fulfilling the inclusion and exclusion criteria • Target variable: Clinical severity status on a 7-point ordinal scale at Day 15 • Estimator: Odds ratio of ATR-002 in addition to standard of care versus placebo in addition to standard of care with 95% confidence interval