Time to clinical improvement (post randomisation) by two points on a seven-category ordinal scale or live discharge from the hospital, whichever comes first The seven-category ordinal scale: 1: Not hospitalised with resumption of normal activities 2: Not hospitalised, but unable to resume normal 3: Hospitalised, not requiring supplemental oxygen 4: Hospitalised, requiring supplemental oxygen 5: Hospitalised, requiring nasal high-flow oxygen therapy, non-invasive mechanical ventilation or both 6: Hospitalised, requiring ECMO (Extra-corporal membrane oxygenation), invasive mechanical ventilation or both 7: Death

Time to clinical improvement (post randomisation) by two points on a seven-category ordinal scale or live discharge from the hospital, whichever comes first The seven-category ordinal scale: 1: Not hospitalised with resumption of normal activities 2: Not hospitalised, but unable to resume normal 3: Hospitalised, not requiring supplemental oxygen 4: Hospitalised, requiring supplemental oxygen 5: Hospitalised, requiring nasal high-flow oxygen therapy, non-invasive mechanical ventilation or both 6: Hospitalised, requiring ECMO (Extra-corporal membrane oxygenation), invasive mechanical ventilation or both 7: Death