Severe hypoxemic respiratory failure expected to die < 72 hours after admission ICU admission < 72 hours Allergy for chloroquine or azithromycin Pregnancy QT-prolongation: pre-existent: QTc males >450ms, QTc females > 470ms at day 1 and at day 2 Myasthenia gravis Epilepsy Severe hypoxemic respiratory failure expected to die < 72 hours after admission ICU admission < 72 hours Allergy for chloroquine or azithromycin Pregnancy QT-prolongation: pre-existent: QTc males >450ms, QTc females > 470ms at day 1 and at day 2 Myasthenia gravis Epilepsy

Severe hypoxemic respiratory failure expected to die < 72 hours after admission ICU admission < 72 hours Allergy for chloroquine or azithromycin Pregnancy QT-prolongation: pre-existent: QTc males >450ms, QTc females > 470ms at day 1 and at day 2 Myasthenia gravis Epilepsy Severe hypoxemic respiratory failure expected to die < 72 hours after admission ICU admission < 72 hours Allergy for chloroquine or azithromycin Pregnancy QT-prolongation: pre-existent: QTc males >450ms, QTc females > 470ms at day 1 and at day 2 Myasthenia gravis Epilepsy