- receipt of pooled immunoglobulin in the past 30 days - contraindication to transfusion or history of prior reactions to transfusion blood products - admission to intensive care unit at any point during hospital course prior to enrollment

- receipt of pooled immunoglobulin in the past 30 days - contraindication to transfusion or history of prior reactions to transfusion blood products - admission to intensive care unit at any point during hospital course prior to enrollment