inclusion criteria: patient is a male or nonpregnant female 18 years of age or older. patient has a positive reverse-transcriptase-polymerase-chain-reaction (rt-pcr) assay for sars-cov-2 in a respiratory tract sample during the current hospital admission. patient has pneumonia confirmed by chest imaging. patient has moderate to severe disease based on the who disease severity scale assessment at the time of randomization defined as: score 4, only those with fio2 > 40% score 5 (non-invasive ventilation or high-flow oxygen) patient has ability to provide informed consent signed by study patient or legally acceptable representative. patient has willingness and ability to comply with study-related procedures/assessments

inclusion criteria: patient is a male or nonpregnant female 18 years of age or older. patient has a positive reverse-transcriptase-polymerase-chain-reaction (rt-pcr) assay for sars-cov-2 in a respiratory tract sample during the current hospital admission. patient has pneumonia confirmed by chest imaging. patient has moderate to severe disease based on the who disease severity scale assessment at the time of randomization defined as: score 4, only those with fio2 > 40% score 5 (non-invasive ventilation or high-flow oxygen) patient has ability to provide informed consent signed by study patient or legally acceptable representative. patient has willingness and ability to comply with study-related procedures/assessments

inclusion criteria: 1. patient is a male or nonpregnant female 18 years of age or older. 2. patient has a positive reverse-transcriptase-polymerase-chain-reaction (rt-pcr) assay for sars-cov-2 in a respiratory tract sample during the current hospital admission. 3. patient has pneumonia confirmed by chest imaging. 4. patient has moderate to severe disease based on the who disease severity scale assessment at the time of randomization defined as: - score 4, only those with fio2 > 40% - score 5 (non-invasive ventilation or high-flow oxygen) 5. patient has ability to provide informed consent signed by study patient or legally acceptable representative. 6. patient has willingness and ability to comply with study-related procedures/assessments

inclusion criteria: 1. patient is a male or nonpregnant female 18 years of age or older. 2. patient has a positive reverse-transcriptase-polymerase-chain-reaction (rt-pcr) assay for sars-cov-2 in a respiratory tract sample during the current hospital admission. 3. patient has pneumonia confirmed by chest imaging. 4. patient has moderate to severe disease based on the who disease severity scale assessment at the time of randomization defined as: - score 4, only those with fio2 > 40% - score 5 (non-invasive ventilation or high-flow oxygen) 5. patient has ability to provide informed consent signed by study patient or legally acceptable representative. 6. patient has willingness and ability to comply with study-related procedures/assessments

inclusion criteria: 1. patient is a male or nonpregnant female 18 years of age or older. 2. patient has a positive reverse-transcriptase-polymerase-chain-reaction (rt-pcr) assay for sars-cov-2 in a respiratory tract sample during the current hospital admission. 3. patient has pneumonia confirmed by chest imaging. 4. patient has score of 5 on the who's disease severity scale assessment 8-point ordinal scale at the time of randomization. 5. patient has ability to provide informed consent signed by study patient or legally acceptable representative. 6. patient has willingness and ability to comply with study-related procedures/assessments

inclusion criteria: 1. patient is a male or nonpregnant female 18 years of age or older. 2. patient has a positive reverse-transcriptase-polymerase-chain-reaction (rt-pcr) assay for sars-cov-2 in a respiratory tract sample during the current hospital admission. 3. patient has pneumonia confirmed by chest imaging. 4. patient has score of 5 on the who's disease severity scale assessment 8-point ordinal scale at the time of randomization. 5. patient has ability to provide informed consent signed by study patient or legally acceptable representative. 6. patient has willingness and ability to comply with study-related procedures/assessments