- history of severe transfusion reaction to plasma products - need for oxygen supplementation - positive test for covid-19 antibodies - chemotherapy-induced neutropenia (anc < 0.5 x 103/mcl) - immunosuppressive medications except for prednisone (or steroid equivalent) > 10 mg daily. - performance status < 50 by kps - pneumonia by radiographic evaluation

- history of severe transfusion reaction to plasma products - need for oxygen supplementation - positive test for covid-19 antibodies - chemotherapy-induced neutropenia (anc < 0.5 x 103/mcl) - immunosuppressive medications except for prednisone (or steroid equivalent) > 10 mg daily. - performance status < 50 by kps - pneumonia by radiographic evaluation