Created at Source Raw Value Validated value
Oct. 26, 2020, 11:31 p.m. usa

- contraindication or allergy to na-831, atazanavir, dexamethasone - current use any antiviral drug or anti-inflammatory drug - concurrent use of another investigational agent - invasive mechanical ventilation - participants who have any severe and/or uncontrolled medical conditions such as: - unstable angina pectoris, - symptomatic congestive heart failure, - myocardial infarction, - cardiac arrhythmias or know prolonged qtc > 470 males, > 480 female on ecg - pulmonary insufficiency, - epilepsy (interaction with chloroquine), - prior retinal eye disease - concurrent malignancy requiring chemotherapy - known chronic kidney disease, egfr < 10 or dialysis - g-6-pd deficiency, if unknown requires g6pd testing prior to enrollment - known porphyria - known myasthenia gravis - currently pregnant or planning on getting pregnant while on study - breast feeding - ast/alt > five times the upper limit of normal uln - bilirubin > five times the uln - magnesium < 1.4 meq/l - calcium < 8.4 mg/dl > 10.6 mg/dl - potassium < 3.3 > 5.5 meg/l

- contraindication or allergy to na-831, atazanavir, dexamethasone - current use any antiviral drug or anti-inflammatory drug - concurrent use of another investigational agent - invasive mechanical ventilation - participants who have any severe and/or uncontrolled medical conditions such as: - unstable angina pectoris, - symptomatic congestive heart failure, - myocardial infarction, - cardiac arrhythmias or know prolonged qtc > 470 males, > 480 female on ecg - pulmonary insufficiency, - epilepsy (interaction with chloroquine), - prior retinal eye disease - concurrent malignancy requiring chemotherapy - known chronic kidney disease, egfr < 10 or dialysis - g-6-pd deficiency, if unknown requires g6pd testing prior to enrollment - known porphyria - known myasthenia gravis - currently pregnant or planning on getting pregnant while on study - breast feeding - ast/alt > five times the upper limit of normal uln - bilirubin > five times the uln - magnesium < 1.4 meq/l - calcium < 8.4 mg/dl > 10.6 mg/dl - potassium < 3.3 > 5.5 meg/l