hospitalized patient or under immediate consideration of doing so patient taking colchicine for other indications patient with history of allergic reaction or sensitivity to colchicine patient with inflammatory bowel disease, gastric ulcer, chronic diarrhea or malabsorption patient with pre-existing progressive neuromuscular disease patient with kidney damage and estimated glomerular filtrate rate <30 ml/m at 1732 patient undergoing chemotherapy for cancer, including haematological malignancies. patients being treated with cyp3a4 and/or glycoprotein inhibitor drugs immunosuppressive treatment history of cirrhosis, chronic active hepatitis, severe chronic disease defined by got or gpt values exceeding 3 times the upper limit of normal. if the investigator considers it, for any reason, to be an inadequate candidate. patient and/or legal representative will not have signed the informed consent form.

hospitalized patient or under immediate consideration of doing so patient taking colchicine for other indications patient with history of allergic reaction or sensitivity to colchicine patient with inflammatory bowel disease, gastric ulcer, chronic diarrhea or malabsorption patient with pre-existing progressive neuromuscular disease patient with kidney damage and estimated glomerular filtrate rate <30 ml/m at 1732 patient undergoing chemotherapy for cancer, including haematological malignancies. patients being treated with cyp3a4 and/or glycoprotein inhibitor drugs immunosuppressive treatment history of cirrhosis, chronic active hepatitis, severe chronic disease defined by got or gpt values exceeding 3 times the upper limit of normal. if the investigator considers it, for any reason, to be an inadequate candidate. patient and/or legal representative will not have signed the informed consent form.

1. hospitalized patient or under immediate consideration of doing so 2. patient taking colchicine for other indications 3. patient with history of allergic reaction or sensitivity to colchicine 4. patient with inflammatory bowel disease, gastric ulcer, chronic diarrhea or malabsorption 5. patient with pre-existing progressive neuromuscular disease 6. patient with kidney damage and estimated glomerular filtrate rate <30 ml/m at 1732 7. patient undergoing chemotherapy for cancer, including haematological malignancies. 8. patients being treated with cyp3a4 and/or glycoprotein inhibitor drugs 9. immunosuppressive treatment 10. history of cirrhosis, chronic active hepatitis, severe chronic disease defined by got or gpt values exceeding 3 times the upper limit of normal. 11. if the investigator considers it, for any reason, to be an inadequate candidate. 12. patient and/or legal representative will not have signed the informed consent form.

1. hospitalized patient or under immediate consideration of doing so 2. patient taking colchicine for other indications 3. patient with history of allergic reaction or sensitivity to colchicine 4. patient with inflammatory bowel disease, gastric ulcer, chronic diarrhea or malabsorption 5. patient with pre-existing progressive neuromuscular disease 6. patient with kidney damage and estimated glomerular filtrate rate <30 ml/m at 1732 7. patient undergoing chemotherapy for cancer, including haematological malignancies. 8. patients being treated with cyp3a4 and/or glycoprotein inhibitor drugs 9. immunosuppressive treatment 10. history of cirrhosis, chronic active hepatitis, severe chronic disease defined by got or gpt values exceeding 3 times the upper limit of normal. 11. if the investigator considers it, for any reason, to be an inadequate candidate. 12. patient and/or legal representative will not have signed the informed consent form.

- patient unable to read and/or understand the informed consent information, read by another person, and the information collected on patient information document. - patient currently hospitalized or under immediate consideration for hospitalization. - patient under colchicine prescription for other pathologies. - patient with a history of an allergic reaction or significant sensitivity to colchicine. - patient with a history of gastrointestinal severe disease such as inflammatory bowel disease, gastric ulcer, chronic diarrhea, or malabsorption. - patient with neuromuscular progressive previous diagnosed disease. - patient with renal disease diagnosis and estimated glomerular filtration less than 30 ml/min in 1.73². - patient with a history of cirrhosis, chronic active hepatitis, or severe liver disease. - patient undergoing chemotherapy for cancer, including hematologic malignancies. - patients who are being treated with cyp3a4 and / or glycoprotein p inhibitor drugs. - immunossuppresive therapy. - history of cirrhosis, active chronic hepatitis, severe chronic disease defined by got or gpt values that exceed 3 times the upper limit of normality. - if the investigator considers that the patient, for any reason, would be an inappropriate candidate.

- patient unable to read and/or understand the informed consent information, read by another person, and the information collected on patient information document. - patient currently hospitalized or under immediate consideration for hospitalization. - patient under colchicine prescription for other pathologies. - patient with a history of an allergic reaction or significant sensitivity to colchicine. - patient with a history of gastrointestinal severe disease such as inflammatory bowel disease, gastric ulcer, chronic diarrhea, or malabsorption. - patient with neuromuscular progressive previous diagnosed disease. - patient with renal disease diagnosis and estimated glomerular filtration less than 30 ml/min in 1.73². - patient with a history of cirrhosis, chronic active hepatitis, or severe liver disease. - patient undergoing chemotherapy for cancer, including hematologic malignancies. - patients who are being treated with cyp3a4 and / or glycoprotein p inhibitor drugs. - immunossuppresive therapy. - history of cirrhosis, active chronic hepatitis, severe chronic disease defined by got or gpt values that exceed 3 times the upper limit of normality. - if the investigator considers that the patient, for any reason, would be an inappropriate candidate.