inclusion criteria: - ii. hospitalized with covid-19 pneumonia, based on chest x-ray or ct scan and iii. evidence of hyperinflammation: il-6>40pg/ml (if available) or crp >2 mg/dl or ferritin >2000 ng/ml and iv. one or more of the following: impending need for requiring invasive or non-invasive mechanical ventilation or shock requiring vasopressor (without evidence of bacterial / fungal infection) or need for extracorporeal membrane oxygenation (ecmo) or severe, refractor ards (pao2/fio2<200 mmhg)

inclusion criteria: - ii. hospitalized with covid-19 pneumonia, based on chest x-ray or ct scan and iii. evidence of hyperinflammation: il-6>40pg/ml (if available) or crp >2 mg/dl or ferritin >2000 ng/ml and iv. one or more of the following: impending need for requiring invasive or non-invasive mechanical ventilation or shock requiring vasopressor (without evidence of bacterial / fungal infection) or need for extracorporeal membrane oxygenation (ecmo) or severe, refractor ards (pao2/fio2<200 mmhg)