[{"arm_notes": "", "treatment_id": null, "treatment_name": "Randomization will be stratified by: 1. Center 2. COVID-19 clinical severity stage Allocation to the intervention group and the control group will be in a 1:1 ratio. Randomization will be blocked in a randomly permuted block size. The intervention group will receive N-Acetylcysteine (NAC) 150 mg/kg every 12 hours for 14 days of admission in addition to the standard of care. The primary route is oral; but the treating team has the option to start or switch to IV Infusion over 1 hour if: 1. The patient can\u2019t tolerate orally. 2. The patient is in shock and gastrointestinal absorption is thought to be impaired. The control group will receive matching normal saline placebo administered in the same schedule and volume as NAC in addition to the standard of care implemented in the hospitals for COVID-19 management. Participants will be followed until they are discharged. No specific laboratory/radiological investigation is required. The result of their usual lab; symptoms progression; clinical severity and outcomes will be collected on a daily basis during hospitalization until discharge.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "1. Center", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "1. The patient can\u2019t tolerate orally.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "2. COVID-19 clinical severity stage", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "2. The patient is in shock and gastrointestinal absorption is thought to be impaired.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 850, "treatment_name": "N-acetylcysteine", "treatment_type": "Respiratory agents", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]

[]

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Randomization will be stratified by: 1. Center 2. COVID-19 clinical severity stage Allocation to the intervention group and the control group will be in a 1:1 ratio. Randomization will be blocked in a randomly permuted block size. The intervention group will receive N-Acetylcysteine (NAC) 150 mg/kg every 12 hours for 14 days of admission in addition to the standard of care. The primary route is oral; but the treating team has the option to start or switch to IV Infusion over 1 hour if: 1. The patient can\u2019t tolerate orally. 2. The patient is in shock and gastrointestinal absorption is thought to be impaired. The control group will receive matching normal saline placebo administered in the same schedule and volume as NAC in addition to the standard of care implemented in the hospitals for COVID-19 management. Participants will be followed until they are discharged. No specific laboratory/radiological investigation is required. The result of their usual lab; symptoms progression; clinical severity and outcomes will be collected on a daily basis during hospitalization until discharge.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "1. Center", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "1. The patient can\u2019t tolerate orally.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "2. COVID-19 clinical severity stage", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "2. The patient is in shock and gastrointestinal absorption is thought to be impaired.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]